GLI1 and neoplasm: Although there was no significant difference in overall survival time between the two groups, the 5-year recurrence rate in the GLI1 high expresser group was 85% compared to 59% in the GLI1 low/non expresser group (P = 0.007, Chi square test), and comparison of Kaplan Meier recurrence-free survival curves showed a tendency toward a more rapid rate of tumor recurrence in patients with GLI1 high expressing tumors (HR = 1.69; 95% CI: 0.9, 3.9; P = 0.09; Figure 2A).