SPRY2 and type 2 diabetes mellitus: Table 2 presents the association of GWAS-identified, T2D-related SNPs with T2D adjusted for BMI, age and sex in our study population. Fourteen variants in twelve gene regions (IGF2BP2, CDKAL1, KCNK15, TP53INP1, SLC30A8, CDKN2A/CDKN2B, CDC123/CAMK1D, HHEX/IDE, KCNQ1, KCNJ11, SPRY2 and HNF1B/TCF2) were significantly associated with T2D. All the SNPs that were significantly associated with T2D in our study (P<0.05), had a direction of association consistent with prior GWAS.