MTOR and neoplasm: Based on observations that rapamycin treatment in SCCVII tumor bearing mice elicits a tumor growth delay correlating with a decrease in the mTOR dependent signaling markers, we next conducted non-invasive imaging experiments to longitudinally monitor tumor oxygen status, tumor anatomy, and tumor blood volume in control and rapamycin treated mice with SCCVII implants by using EPRI and MRI.