Notably, we found that the genes involved in the Wnt pathway were enriched (P = 0.026; Table 6, Figure S1), and four genes (FZD5, LRP6, PPP2R1B, and TBL1XR1) in this pathway switched to proximal APA sites in nasal polyp tissue. This evidence concerns the gene TBL1XR1 and nasal cavity polyp.