Indeed, in transiently transfected (human) SK-N-MC neuroblastoma cells, LOC389023 showed a specific association with H3K4-trimethylated nucleosomes and SUZ12 (Figure 5D), a zinc finger protein and core component of PRC2 previously shown to interact with stem loop motifs similar to the one shown in Figure 5C, [37]. The gene discussed is ZNF146; the disease is neuroblastoma.