During this preliminary study, we investigated expression pattern of 6 MBC autoantigens, including secretory protein LGALS3BP, 2 nuclear proteins (RAD50, FAM50A), one cytoplasmic protein (PABPC4) and 2 tratscription factors (RBPJ, LRRFIP1), in different histological types of breast cancer and non-cancerous tissue samples by immunohistochemical analysis. The gene discussed is RAD50; the disease is breast carcinoma.