Many breast cancer antigens have been reported to be overexpressed at protein level in breast tumors; these include MUC1[19], HER2/neu[20], P53[21], HSP-27[22,23], GIPC-1[24], fibulin 1[25] and cyclins B1[26], D1[27] and E[28]. Here, ERBB2 is linked to breast cancer.