GLO1 and cancer: The basic biochemistry of GLO1 has been reviewed elsewhere (Thornalley, 1990, 1993, 2003b), as have its roles in cancer (Thornalley, 2003a; Thornalley and Rabbani, 2011) and diabetic complications (Brownlee, 2001; Ahmed and Thornalley, 2007; Schleicher and Friess, 2007; Jack and Wright, 2012; Rabbani and Thornalley, 2012).