Apart from the Bcl-2 family members, we and others recently reported that the Ets protein, Ets-related gene (Erg) is induced by GC in the resistant ALL CEM C1–15 cells and may be a crucial GR target for determining GC resistance (Geng and Vedeckis, 2005; Baldus et al., 2006; Thoms et al., 2011; Tsuzuki et al., 2011). This evidence concerns the gene NR3C1 and acute lymphoblastic leukemia.