Protein phosphatase 2A (PP2A) is a tumour suppressor enzyme (Eichhorn et al, 2009; Westermarck & Hahn, 2008) involved in the regulation of oncoproteins, such as c-Myc (Yeh et al, 2004) and Bcr-Abl (Salas et al, 2011), in various cancers including lung cancers and CML, respectively. The gene discussed is PTPA; the disease is lung cancer.