CNTNAP2 and autism: Sex effects are evident at onset, with greater risk for late onset for males[12]; males account for the CNTNAP2 variants’ associations with autism age at first words[67]; and males with higher levels of umbilical cord blood testosterone were at increased risk for language delay during the first 3 years of life, although testosterone increase may be a protective factor for females[71] Nutritional risks are reported for language impairments in childhood.