ERBB2 and metastatic neoplasm: These results contrast with a study, which utilised immunohistochemistry to evaluate HER2 status in residual disease in the breasts of 15 patients receiving anthracycline-based neoadjuvant therapy (trastuzumab was not given) and 44 patients with metastatic disease who underwent surgical resection or biopsy of localised liver or lung metastases [18].