She put special emphasis on Fc-mediated effects and concentrated on the impact of IVIG glycosylation as well as the role of Fcgamma receptor IIb in animal models of rheumatoid arthritis and immune thrombocytopenia (ITP).I In addition, samples from patients suffering from chronic inflammatory demyelinating polyneuropathy (CIDP) treated with IVIG were analyzed. Here, FCGR2B is linked to autoimmune thrombocytopenic purpura.