Human 5-lipoxygenase (5-LOX) is one of the key anti-inflammatory drug targets due to its key role in leukotrienes biosynthesis which show that leukotrienes [40] and low-grade inflammation might be a common denominator of some psychiatric diseases as major and postpartum depression, schizophrenia, and autism [41]. This evidence concerns the gene ALOX5 and schizophrenia.