These processes are well described in a recent review.58 A study performed in Indonesia showed that patients with P. falciparum and P. vivax malaria had lower platelet count, higher von Willebrand factor (VWF) concentration, lower ADAMTS13 activity and ADAMTS13 antigen concentrations.59 Higher VWF seems to correlate with platelet binding, leading to thrombocytopenia. The gene discussed is ADAMTS13; the disease is Thrombocytopenia.