Rarely, acute renal failure has been associated to rhabdomyolysis in P. falciparum and P.vivax infections, probably due to the sequestration of parasitized red cells in the skeletal capillaries and consequent vessels occlusion.108 In the pathogenesis of ARF related to rhabdomyolysis, the myoglobin nephrotoxic effect play the principal role; hypovolemia, hypotension, fever, acidosis and the use of non-steroidal anti-inflammatory drugs may worsened the renal function.109,110. This evidence concerns the gene MB and acute kidney injury.