It is interesting to note that virus-mediated changes in hnRNP C expression or localization would result in the inhibition of interferon (IFN) signaling since this hnRNP has been proved to be involved in phospho-STAT1 nuclear import, so a reduced level of hnRNP C in WE-infected cells may contribute to the severity of the infection [63,67]. Here, IFNA1 is linked to infection.