BCL2 and infection: Interestingly, overexpression of Bcl-2 in white blood cells, which can block the intrinsic apoptotic pathway via inhibition of mitochondrial cytochrome-c release, also rescued lymphocytes from apoptosis after infection, suggesting that both intrinsic and extrinsic apoptotic pathways are utilized to induce lymphocyte apoptosis in maEBOV infection.