CACNA1B and neuroblastoma: It was therefore also very pleasing to find that ω-conotoxin GVIA mimetics (7c, 7d, 8c, 8d) identified to be active in the radioligand displacement assay also induced functional inhibition of intracellular calcium responses in SH-SY5Y neuroblastoma cells and calcium currents in HEK293 cells stably expressing human Cav2.2 channels.