LTB4R and asthma: The aims of this study were to 1) investigate the gene structure of human LTB4R1 and LTB4R2 in cells and tissues relevant to asthma; 2) determine the extent and nature of polymorphic variation across the receptor locus and 3) determine if LTB4R polymorphisms were associated with asthma, lung function and disease severity in asthma families and adult asthma subjects.