The corresponding protein levels were also increased; PEPCK by 59±7% (p<0.002) in UN pups and G6Pase by 24±3% (p<0.03) in DEX and by 38±3% (p<0.01) in UN pups (Fig. 3B and 3C), suggesting a precocious elevation in gluconeogenesis and liver glucose output in these two IUGR rat models. Here, G6PC1 is linked to fetal growth restriction.