The analysis also revealed that the pyrin-related genes including Mediterranean fever (Medv), myeloid cell nuclear differentiation antigen (Mnda), and interferon activated genes 204 and 205 (Ifi204, Ifi205) were significantly induced due to lack of hepatic RXRα, but they do not have RXRα binding sites (Figure 4A). This evidence concerns the gene MEFV and brucellosis.