The CCL2(MCP-1)-CCR2 axis plays a pivotal role in monocyte-macrophage trafficking to sites of inflammation and has been implicated in the pathogenesis of various disease processes such as cardiovascular disease, diabetic nephropathy, rheumatoid arthritis, and several infectious diseases [1], [2], [3], [4], [5], [6], [7], [8], [9]. This evidence concerns the gene CCL2 and rheumatoid arthritis.