Also, rs3092920 CD154 polymorphism is in high linkage disequilibrium (r2 = 0.97) with a microsatellite located in 3′-UTR that has been associated in Spanish population with SLE [27], another autoimmune disease associated with accelerated atherosclerosis and increased risk of CV complications, and with RA susceptibility [28]. Here, CD40LG is linked to rheumatoid arthritis.