Interestingly, the PADI2 variant meta-analysis demonstrated a possible novel association of the PADI2 rs1005753 variant with RA, both in the allelic model (ORoverall = 0.88, 95% CI = 0.77 to 0.99, P = 0.04) and in the dominant/recessive genotype model (ORoverall = 0.84, 95% CI = 0.72 to 0.99, P = 0.04) (Figure 1). Here, PADI2 is linked to rheumatoid arthritis.