CXCL8 and hemolytic-uremic syndrome: Indeed, treatment of the intestinal cell line HCT-8 results in the induction of the potent neutrophil chemo-attractant interleukin-8 (IL-8) (Thorpe et al., 1999b), and there is a correlation between numbers of PMNs and increased IL-8 in both patients with HUS and rabbits treated with Stxs (Fitzpatrick et al., 1992; Garcia et al., 2008).