For example, aberrant formation of fusion proteins through chromosomal translocations of HATs such as E1A-binding protein p300 (EP300), nuclear receptor coactivator-2 (NCOA2), MYST3 [histone acetyltransferase (monocytic leukemia) 3] and MYST4 have been identified in hematological cancers (Yang, 2004). Here, EP300 is linked to hematopoietic and lymphoid cell neoplasm.