Confirmation that this enhanced DHF-like disease and mortality resulted from ADE was supported by passive transfer of enhancing EDIIFP MAb 4G2 and by rescue from enhanced mortality by passive transfer of 4G2 F(ab′)2 fragment unable to bind FcγR (Balsitis et al., 2010). The gene discussed is FCGR2A; the disease is acute disseminated encephalomyelitis.