In sum, hyperglycemia conditions occur in an elevated proportion of individuals suffering of acromegaly, Cushing’s disease or NET and accordingly, it has been proposed that regular blood glucose testing and insulin analogs will be required, particularly when SST analogs are therapeutically used in these pathologies (Resmini et al., 2009; Colao et al., 2012). The gene discussed is INS; the disease is acromegaly.