In cultured human cell lines, MSX2 expression was found in pancreatic cancer cell lines while it was not observed in human normal pancreatic duct epithelial cell line (HPDE) nor in pancreatic stellate cells (PSC) (Table 1) (Satoh et al., 2008a, 2010, 2011). This evidence concerns the gene MSX2 and pancreatic neoplasm.