Overall, RBM5 was expressed in 10 of 11 (90.9%) normal prostate tissues, and the cytoplasmic/nuclear ratio of the staining was about 50%; while the RBM5 was expressed in two of 12 prostate cancer specimens (16.7%), and the cytoplasmic/nuclear ratio of the staining was about 10%. Here, RBM5 is linked to Familial prostate cancer.