In those papers, heterologous cell lines (SCLC, HeLa, and HEK293) were transfected with promoter deletion constructs of the Avp gene and the authors reported osmotic regulatory sites that are located in the 5′ flanking sequence between −1500 and −532 bp upstream of the TSS in the Avp gene [54], [55]. This evidence concerns the gene AVP and small cell lung carcinoma.