Multivariable Cox regression analysis was performed to assess the prognostic value of admission HR after adjusting for age, sex, the medical history of hypertension, heart failure, myocardial infarction, stroke, Killip class, medications and procedures in-hospital (Insulin, β-blockers, ACEI, lipid-lowering drugs, and PCI). The gene discussed is INS; the disease is myocardial infarction.