KIT and gastrointestinal stromal tumor: It is strongly suggested that those with suspected gastric nodules of less than 20 mm in size are also referred tfor resection if any of the following is present: 1) nodule with signs of irregular margin, ulceration, bleeding or increase in size during follow-up; 2) presence of cystic change, necrosis, heterogeneous echogenecity, lobulation, poor patient compliance with follow-up; or 3) diagnostic confirmation of GIST by FNAB or presence of KIT-positive tumor.