When we compared FoxP3 expression in CD4 Treg cells and CD8 Treg cells with non-regulatory T cells (median FoxP3 expression in non-regulatory T cells: MM-0.0072, HD-0.0058) from MM patients and healthy donors; results showed that CD4 Treg cells had significantly increased expression of FoxP3 compared to non-regulatory T cells (MM: P = 0.019, HD: P = 0.019). The gene discussed is FOXP3; the disease is Miyoshi myopathy.