A comparative analysis of corresponding immunohistochemical results for p-Hsp27 and the EMT-associated markers taken from the tumor nodules of the mice after treatment with Qu combined with Cis revealed a marked downregulation of p-Hsp27, vimentin, Twist-1, and fascin-1 and upregulation of E-cadherin in DRSPs compared with the group that did not receive treatment (Figure 4D). Here, VIM is linked to neoplasm.