Compared with HCs, the phenotype frequencies of the DRB1*0405 and DPB1*0301 alleles were significantly higher in MS patients (pcorr = 0.0013, OR = 2.230, 95% CI = 1.494–3.330, and pcorr = 0.0007, OR = 3.715, 95% CI = 1.879–7.347, respectively). This evidence concerns the gene HLA-DRB1 and myeloid sarcoma.