LEF1 and B-cell chronic lymphocytic leukemia: We confirm the overexpression of LEF-1 in CLL B cells compared with B cells from healthy donors (data not shown), as previously reported [33], but we also observed upregulation of LEF-1 and other genes involved in the Wnt signaling pathway in 17p-, 11q- and 13q-H patients in comparison with 13q-L cases.