To better study the cellular location and the relationship between DJ-1 and PTEN in SSCCs, fluorescent immunohistochemistry was performed, and the results showed that strong expression of DJ-1 is found in cytoplasm of SSCC tumor cells, while poor staining of PTEN was observed in cytoplasm of SSCC tumor cells, and that strong expression of PTEN is found in cytoplasm of adjacent non-cancerous cells, while poor staining of DJ-1 was observed in cytoplasm of adjacent non-cancerous cells (Figure1B). The gene discussed is PARK7; the disease is neoplasm.