Mutations in the SLC26A4 gene are found in not only patients with Pendred syndrome (PS; OMIM # 274600), but also in individuals afflicted with nonsyndromic hearing loss (NSHL) with enlarged vestibular aqueduct (EVA) at the DFNB4 locus[5,7-9]. The gene discussed is SLC26A4; the disease is nodular sclerosis classical Hodgkin lymphoma.