This set encompassed 1,158/2,064 triple-negative BC copy-number dependent genes as determined by Turner [31], and included genes such as transcriptional regulators (n=98), kinases (n=47), phosphatases (n=24) and transmembrane receptors (n=5), as well as biomarkers for diagnosis (n=42), prognosis (n=14), disease progression (n=7) and known drug targets (n=20) (Additional file 5 Table S4). This evidence concerns the gene NRP1 and breast cancer.