The TLR2, TLR3 rs5743315/AC and TLR4 polymorphisms were equally distributed in the two groups regardless of the clinical diagnosis, whereas the TLR3 rs5743313/CT polymorphism was found in all of the children with pneumonia and influenza infection, but in a significantly smaller number of those A/H1N1/2009 influenza without pneumonia without pneumonia (<0.0001). This evidence concerns the gene TLR3 and pneumonia.