SOD1 and Venous thrombosis: On the model of arterial thrombosis in rats induced via treatment of the vessel witha saturated solution of iron (II) chloride, the bienzyme conjugate SOD-CHS-CATexhibited an antithrombotic effect when administered at doses lower by two orders ofmagnitude than those of the native SOD and CAT, and lower by an order of magnitudesthan those of SOD and CAT (or their mixture) modified with chondroitin sulphate (Fig. 4 ) [50].