CXCL9 and Crohn disease: Although Bruck et al [35] failed to observe any association between the CXCL9 rs10336 CT polymorphism and type 1 diabetes, the CXCL9 rs2276886 GA polymorphic variant was associated with a reduced risk for pediatric Crohn's disease; significantly, CXCL9 was found to be overexpressed in Crohn's disease gut tissue [63].