ROC-based assessment of the individual VEGF family members as biomarkers for colon cancer identified overexpression of PlGF (AUC 0.9342) as the most effective mRNA-marker for samples obtained by biopsy with VEGF-A (AUC 0.8760) and VEGF-C AUC 0.8977) following as close seconds (Figure 4). This evidence concerns the gene VEGFC and colonic neoplasm.