Malaria parasites possess six peroxidases localized in the cytoplasm, mitochondrion, apicoplast and nucleus: a 1-Cys Prx, two typical 2-Cys Prxs, a 1-Cys antioxidant protein (AOP), a Prx family with unusual biochemical characteristics and a glutathione (GSH) peroxidase-like thioredoxin peroxidase (TPxGl) [7-9]. The gene discussed is PRX; the disease is malaria.