PDGFRB and colorectal carcinoma: SNP B19, present in 4 CRC cell lines (LS174T, LS180, SW48, COLO205) and in 58% of patients, had a substantial impact on overall survival, with 5-year survival rates of 51% for patients with PDGFR B19 wild type tumors versus 17% for those harboring the SNP variant (c.2601A>G).