TNF and Urinary incontinence: There were no significant differences in either intrathecal immunoglobulin levels (Igloc) or cytokine concentrations (IL-10, IFN-γ, TNF-α, TGF-β or IL-6) in relation to the presence or absence of gait ataxia, tremors, urinary incontinence, although cases with facial nerve palsies exhibited a slight increase in intrathecal IgA concentration (median (IQR) 0.0 (0.0–4.6) mg/l versus 0.0 (0.0–0.8) mg/l p<0.05).