There was a highly significant positive correlation between hepatic cellular infiltrates and the copy number of dnTGFβRII transgene (r = 0.9342, p<0.0001), indicating that abrogation of TGFβ signaling by higher copy number of dnTGFβRII contributes to the emergence of T cell lymphoma-like T cell infiltration. The gene discussed is TGFB1; the disease is T-cell non-Hodgkin lymphoma.