IL6 and lymphoma: Since the lymphoma-like HMNCs are seen in approximately one third of the dnTGFβRII+ IL-6−/− mice generated by intercross breeding that resulted in a mixture of littermates with hemizygous (+/−) and homozygous (+/+) dnTGFβRII gene, but not seen in pure hemizygous dnTGFβRII+/− IL-6−/− litters generated without intercrossing, the results also suggest that the lymphoma-like T cell infiltration occurred in mice with the homozygous dnTGFβRII gene.