Our results demonstrate that, of the 65 factors analyzed and related to the inflammatory process and tumor progression, those related to MMP-11 expression by MICs in the intratumoral stroma were IL-1, −5, −6, −8, −17, −18, MMP-1, TIMP-1, ADAM-8, −10, −15, −23, ADAMTS-1, −2, −15, CCL-3, Annexin A2, IFNβ, Claudin3, IRAK-4, MyD88 and NFκB. The gene discussed is IRAK4; the disease is neoplasm.