We analyzed by real-time PCR the expression of the selected factors (IL-1, −5, −6 and −17, IFNβ and NFκB) more differentially expressed in the preliminary screening, in a wider tumor population consisting of three differentiated groups according to MMP-11 expression by MICs and to distant metastasis development (n = 15 in each group) (Figure 3). Here, IFNB1 is linked to neoplasm.