CD8A and infection: To assess the cytotoxicity of these primed CD8+ T cells purified CD8+ T cells were isolated from SLA-CpG-DCs vaccinated and CXCL10 depleted SLA-CpG-DCs vaccinated L. donovani infected mice 28 days following infection and were co-cultured with autologous L.donovani-infected macrophages in a 10∶1 ratio.