Given the vital role Foxm1 plays during cardiac embryogenesis as well as the predisposition for end of life cardiac hypertrophy in αMHC-Cre/Foxm1fl/fl mice, we also investigated the importance of Foxm1 in cardiac pathology using a mouse model of cardiac hypertrophy induced by aortic banding. Here, FOXM1 is linked to cardiac hypertrophy.